MOTS-c
MOTS-c is a mitochondrial-derived peptide composed of 16 amino acids, encoded by the 12S rRNA region of mitochondrial DNA. This peptide is supplied in liquid form with a purity level of ≥99%, making it suitable for in-vitro and laboratory research applications.
$54.99
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Overview
MOTS-c is currently under investigation for its potential roles in metabolic regulation, aging, and stress responses. Its unique mitochondrial origin makes it a promising subject in the study of cellular homeostasis and chronic metabolic disorders.
Product Research
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Metabolic Regulation and Insulin Sensitivity
MOTS-c has been shown to improve glucose metabolism in skeletal muscle, which may be beneficial in research involving insulin resistance, type 2 diabetes, and obesity [1].
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Cardiovascular Health
In preclinical trials, MOTS-c administration attenuated cardiac dysfunction and remodeling, indicating potential therapeutic relevance in studies of heart failure and myocardial injury [2].
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Exercise Physiology
Levels of MOTS-c have been found to increase in skeletal muscle following long-term endurance training, suggesting a role in exercise-induced metabolic adaptation and mitochondrial function [3].
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Aging and Muscle Function
MOTS-c levels in circulation tend to decrease with age, but its expression in skeletal muscle increases. These shifts have been associated with muscle quality in aging populations, making it valuable for gerontological research [4].
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Inflammation and Immune Response
MOTS-c has demonstrated anti-inflammatory effects by modulating macrophage activity and enhancing phagocytosis in experimental models of colitis and inflammation [5].
Disclaimer
This product is intended for laboratory research and development purposes only. It is not approved for human consumption, medical, or veterinary use. All information provided is for scientific reference only. Use under the supervision of qualified professionals in appropriate research settings.
Referenced Citations
- MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation – PubMed
- Mitochondrial-derived peptide MOTS-c prevents the development of heart failure – PubMed
- MOTS-c increases in skeletal muscle following long-term physical activity – PubMed
- Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men – PubMed
- Orally administered MOTS-c analogue ameliorates dextran sulfate sodium-induced colitis in mice – PubMed
Related Products
Overview
MOTS-c is currently under investigation for its potential roles in metabolic regulation, aging, and stress responses. Its unique mitochondrial origin makes it a promising subject in the study of cellular homeostasis and chronic metabolic disorders.
Product Research
-
Metabolic Regulation and Insulin Sensitivity
MOTS-c has been shown to improve glucose metabolism in skeletal muscle, which may be beneficial in research involving insulin resistance, type 2 diabetes, and obesity [1].
-
Cardiovascular Health
In preclinical trials, MOTS-c administration attenuated cardiac dysfunction and remodeling, indicating potential therapeutic relevance in studies of heart failure and myocardial injury [2].
-
Exercise Physiology
Levels of MOTS-c have been found to increase in skeletal muscle following long-term endurance training, suggesting a role in exercise-induced metabolic adaptation and mitochondrial function [3].
-
Aging and Muscle Function
MOTS-c levels in circulation tend to decrease with age, but its expression in skeletal muscle increases. These shifts have been associated with muscle quality in aging populations, making it valuable for gerontological research [4].
-
Inflammation and Immune Response
MOTS-c has demonstrated anti-inflammatory effects by modulating macrophage activity and enhancing phagocytosis in experimental models of colitis and inflammation [5].
Disclaimer
This product is intended for laboratory research and development purposes only. It is not approved for human consumption, medical, or veterinary use. All information provided is for scientific reference only. Use under the supervision of qualified professionals in appropriate research settings.
Referenced Citations
- MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation – PubMed
- Mitochondrial-derived peptide MOTS-c prevents the development of heart failure – PubMed
- MOTS-c increases in skeletal muscle following long-term physical activity – PubMed
- Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men – PubMed
- Orally administered MOTS-c analogue ameliorates dextran sulfate sodium-induced colitis in mice – PubMed
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